Research and formulation development

The Academy of Medical Sciences, Vietnam (AMS Vietnam) conducts advanced research and formulation development in cosmetics with the objective of creating products that are safe, effective, scientifically substantiated, and aligned with international regulatory and quality standards. Cosmetic research at AMS Vietnam integrates biomedical science, dermatological knowledge, pharmaceutical technology, and applied chemistry to support innovation across skincare, haircare, and personal care products.

Our work focuses on transforming scientific evidence into high-quality cosmetic formulations that meet both functional performance requirements and consumer safety expectations. Through rigorous research methodologies and controlled formulation processes, AMS Vietnam supports manufacturers, brands, and partners throughout the cosmetic product development lifecycle.

Research and formulation development at AMS Vietnam are grounded in evidence-based science and a deep understanding of skin biology. Our research approach emphasizes:

• Mechanistic understanding of skin structure and function
• Interaction between cosmetic ingredients and biological systems
• Safety, stability, and performance of formulations
• Reproducibility, traceability, and regulatory compliance

By combining theoretical research with applied formulation science, the Academy ensures that cosmetic products are developed on a robust scientific foundation rather than empirical assumptions alone.

A critical component of cosmetic formulation development is the scientific evaluation and selection of ingredients. AMS Vietnam conducts systematic research on both natural and synthetic cosmetic ingredients, including:

• Botanical extracts and bioactive compounds
• Functional excipients and delivery systems
• Preservatives, emulsifiers, and stabilizers
• Fragrances, colorants, and sensory modifiers

Ingredient research focuses on physicochemical properties, biological compatibility, safety profiles, and functional performance. Particular attention is given to ingredient interactions, stability under different conditions, and suitability for various skin types and usage scenarios.

Where applicable, traditional medicinal knowledge is scientifically evaluated and integrated with modern cosmetic science to develop formulations that are innovative while remaining evidence-based.

Formulation development at AMS Vietnam follows a structured and iterative process designed to optimize safety, stability, and efficacy. This process includes:

• Defining functional objectives and product claims
• Selecting appropriate formulation systems
• Optimizing ingredient concentrations and ratios
• Evaluating physicochemical properties such as pH, viscosity, and texture
• Assessing sensory attributes and user experience

Formulations are developed across a wide range of cosmetic product categories, including creams, lotions, serums, cleansers, masks, sunscreens, shampoos, and other personal care products. Advanced formulation techniques are applied to improve ingredient delivery, enhance stability, and ensure consistent performance.

Ensuring product stability is essential for cosmetic quality and consumer safety. AMS Vietnam conducts comprehensive stability and compatibility studies to evaluate how formulations perform over time and under varying environmental conditions.

These studies assess parameters such as:

• Physical stability and phase separation
• Chemical stability of active ingredients
• Microbiological integrity
• Packaging compatibility and material interactions

Data generated from stability testing inform formulation refinement, shelf-life determination, and packaging selection. This evidence-based approach supports product reliability and regulatory documentation.

Safety is a fundamental principle in all cosmetic research activities at AMS Vietnam. Formulation development is conducted in compliance with applicable cosmetic regulations and safety guidelines.

Safety-oriented research includes:

• Ingredient safety assessment based on toxicological data
• Evaluation of irritation and sensitization potential
• Avoidance of prohibited or restricted substances
• Optimization of preservative systems to minimize risk

By integrating safety considerations at every stage of formulation development, AMS Vietnam helps ensure that cosmetic products are suitable for intended use and target populations.

AMS Vietnam actively explores innovative formulation technologies to enhance cosmetic performance and differentiation. Research areas include:

• Encapsulation and controlled-release systems
• Nanotechnology and microemulsion systems
• Functional biopolymers and biomimetic ingredients
• Sustainable and environmentally responsible formulation approaches

These innovations aim to improve ingredient stability, enhance skin delivery, reduce irritation potential, and support modern consumer expectations regarding sustainability and product performance.

Consistency and reproducibility are essential in cosmetic formulation development. AMS Vietnam applies standardized protocols and quality control measures throughout the research process to ensure that formulations can be reliably scaled from laboratory development to production environments.

Standardization activities include:

• Establishing formulation specifications
• Defining critical quality attributes
• Documenting formulation procedures and controls
• Supporting technology transfer to manufacturing partners

This systematic approach reduces variability and supports efficient commercialization.

Cosmetic research and formulation development at AMS Vietnam are conducted with close attention to regulatory frameworks. While regulations may vary by market, the Academy supports formulation development that aligns with widely recognized international standards.

Regulatory-oriented research outputs may include:

• Ingredient dossiers and formulation summaries
• Safety justification documentation
• Stability and compatibility data packages
• Scientific substantiation for cosmetic claims

These materials support product registration, market authorization, and compliance with regulatory requirements in domestic and international markets.

AMS Vietnam collaborates with cosmetic manufacturers, brands, research institutions, and suppliers to deliver customized formulation development solutions. Collaboration models range from early-stage concept development to formulation optimization and reformulation of existing products.

Through scientific consultation and joint research projects, the Academy contributes independent expertise that enhances product credibility, innovation capacity, and scientific transparency.

All cosmetic research conducted at AMS Vietnam adheres to principles of scientific integrity, transparency, and ethical responsibility. Research processes are documented, data are systematically reviewed, and conclusions are supported by empirical evidence.

This commitment ensures that cosmetic formulations developed with AMS Vietnam’s involvement meet high standards of credibility and professional accountability.

The Academy of Medical Sciences, Vietnam continues to expand its cosmetic research capabilities in response to evolving scientific knowledge, regulatory expectations, and consumer needs. Future priorities include advanced skin science research, sustainable formulation strategies, and integration of digital tools for formulation optimization.

By combining rigorous science with applied innovation, AMS Vietnam aims to serve as a trusted research partner in cosmetic formulation development, contributing to safer, more effective, and scientifically validated cosmetic products.